top of page

References Resume


A) Effects and safety of Pueraria mirifica on lipid profiles and biochemical markers of bone turnover rates in healthy postmenopausal women.Manonai J, Chittacharoen A, Udomsubpayakul U, Theppisai H, Theppisai U.
Department of Obstetrics and Gynaecology, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.


B)  Beneficial Estrogenic Effects of Pueraria mirifica on Vaginal Health in Postmenopausal Women Manonai J, Chittacharoen A, Theppisai U, Theppisai H. Effect of Pueraria mirifica on vaginal health. Menopause. 2007;14(5):919-924


C) Clinical Trial of the Phytoestrogen-rich Herb, Pueraria mirifica of Symptoms as a Crude Drug in the Treatment of in Menopausal Women *Division of Urology, Department of Surgery,   Verasing Muangman M.D.*, Wichai Cherdshewasart PHD** * Division of Urology, Department of Surgery,  Ra mathibodi Hospital, Mahidol University,  Bangkok 10400, **Department of Biology, Faculty of Science,  Chulalongkorn University, Bangkok 10330, Thailand.


D) Development of Pueraria Mirifica (Thai Herb) for ERT and Inhibits Neurotoxic in Alzheimer’s Model in Vitro Sayan Sawatsri*, Wanphen Yamkunthong*, Neil Sidell**  * Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand ** Emory University School of Medicine, GYN-OB Dept., Research Div., Atlanta, GA, USA

1. Lamlertkittikul S, Chandeying V. Efficacy and safety of Pueraria mirifica (Kwao Kruea Khao) for the treatment of vasomotor symptoms in perimenopausal women: Phase II Study. J Med Assoc Thai. 2004 Jan;87(1):33-40.

2. Sawatsri, S., Juntayanee, B., Jitpatima, S., Boonnao, P., Kampoo, C., Ayuttaya, N., Wongyai, S. and Sidell, N. Pueraria mirifica promotes fibroblasts in normal breast cells and inhibits estrogen-dependent breast cancer cells. Unpublished, 2001

3. Medicinal Plant Research Institute, Dept. of Medical Sciences, Ministry of Public Health, Thailand.

4. Arjmandi BH. The role of phytoestrogens in the prevention and treatment of osteoporosis in ovarian hormone deficiency. J Am Coll Nutr. 2001 Oct;20(5 Suppl):398S-402S; discussion 417S-420S.

5. Anthony C. Dweck. FLS FRSC FRSH The Pueraria family with special interest in Pueraria mirifica. Personal Care Magazine 3, 1, p.7-10. (2002).

6. Asano K et al. Effect of Eleutherococcus senticosus extracts on human physical working capacity. Planta Medica, 1986, 4:175-177.

7. Bohn B et al. Flow-cytometric studies with Eleutherococcus senticosus extract as an immunomodulatory agent. Arzneimittel-Forschung, 1987, 37:1193-1196.

8. V. A. Kurkin, A. V. Dubishchev, V. N. Ezhkov, I. N. Titova and E. V. AvdeevaV. Antidepressant activity of some phytopharmaceuticals and phenylpropanoids Pharmaceutical Chemistry Journal Volume 40, Number 11, 614-619, DOI: 10.1007/s11094-006-0205-5

9. Medon PJ et al. Effects of Eleutherococcus senticosus extracts on hexobarbital metabolism in vivo and in vitro. Journal of Ethnopharmacology, 1984, 10:235-241.

10. Arushanian EB, Baida OA, Mastiagin SS, Popova AP, Shikina IB. [Effect of eleutherococcus on short-term memory and visual perception in healthy humans] Eksp Klin Farmakol. 2003 Sep-Oct;66(5):10-3.

11. Cherdshewasart W, Nimsakul N. Clinical trial of Butea superba, an alternative herbal treatment for erectile dysfunction. Asian J Androl. 2003 Sep;5(3):243-6.

12. Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med. 2002 Apr;8(2):143-52.

13. Stephen B. Strum, MD, FACP, and William Faloon Beta-Sitosterol and the Aging Prostate Gland http://www.diet4u.org/articulos/beta.pdf

14. Si H, Liu D. Phytochemical genistein in the regulation of vascular function: new insights. Curr Med Chem. 2007;14(24):2581-9.

15. Gabay O, Sanchez C, Salvat C, Chevy F, Breton M, Nourissat G, Wolf C, Jacques C, Berenbaum F. Stigmasterol: a phytosterol with potential anti-osteoarthritic properties. Osteoarthritis Cartilage. 2010 Jan;18(1):106-16. Epub 2009 Sep 15.

16. Nakatani K, Atsumi M, Arakawa T, Oosawa K, Shimura S, Nakahata N and Ohizumi Y Inhibitions of histamine release and prostaglandin E2 synthesis by mangosteen, a Thai medicinal plant. Biological and Pharmaceutical Bulletin. 2002 September;25(9):1137-41

17. Mahabusarakam W, Proudfoot J, Taylor W, Croft K. Inhibition of lipoprotein oxidation by prenylated xanthones derived from mangostin. Free Radic Res. 2000 Nov;33(5):643-59

18. Arichi, Shigeru, et al. “Saponins of Gynostemma pentaphyllum as neoplasm inhibitors.” Jpn. Kokai Tokkyo Koho. Jpn. 1985. 60(105): 627.

19. Hou, J., et al. “Effects of Gynostemma pentaphyllum makino on the immunological function of cancer patients.” Journal of Traditional Chinese Medicine (K9K). 1991. 11(1): 47-52.

20. Li, T.H., et al. “Therapeutic effect of jiaogulan on 20 patients with cardio-esophageal carcinoma.” Hebei Zhong Yi. Chinese. 1992. 14(4): 4.

21. Cheng, Y.F., et al. “Clinical study on the protective effect of jiaogulan oral liquid against liver damage.” Zhejiang Zhong Yi Za Zhi. Chinese. 1990. 25(6): 247.

22. Duan, J.Y., et al. “Anti-inflammatory and Immune functions of jiaogulan.” Zhong Cheng Yao. Chinese. 1990. 12(5): 45.

23. Anthony C. Dweck FLS FRSH FRSC A review of Mangosteen (Garcinia mangostana) Linn. http://www.dweckdata.com/Published_papers/Garcinia_mangostana.pdf

24. Rao TP, Sakaguchi N, Juneja LR, Wada E, Yokozawa T. Amla (Emblica officinalis Gaertn.) extracts reduce oxidative stress in streptozotocin-induced diabetic rats. J Med Food. 2005 Fall;8(3):362-8.

25. Bhattacharya SK, Bhattacharya A, Sairam K, Ghosal S. Effect of bioactive tannoid principles of Emblica officinalis on ischemia-reperfusion-induced oxidative stress in rat heart. Phytomedicine. 2002 Mar;9(2):171-4.

26. Jacob A, Pandey M, Kapoor S, Saroja R. Effect of the Indian gooseberry (amla) on serum cholesterol levels in men aged 35-55 years. Eur J Clin Nutr. 1988 Nov;42(11):939-44.

27. Shamim A. Qureshi,Warda Asad and Viqar Sultana The Effect of Phyllantus emblica Linn on Type - II Diabetes, Triglycerides and Liver - Specific Enzyme Pakistan Journal of Nutrition 8 (2): 125-128, 2009

28. Bandyopadhyay SK, Pakrashi SC, Pakrashi A. The role of antioxidant activity of Phyllanthus emblica fruits on prevention from indomethacin induced gastric ulcer. J Ethnopharmacol. 2000 May;70(2):171-6.

29. Ingham, JL., Tahara, S. and Dziedzic, SZ. (1986) A chemical investigation of Pueraria mirifica roots, Zeitschrift fur Naturforschung Serie C, 41, 403-408.

30. A. Manosroi, J. Manosroi Determination of bioactive compounds in roots of different ages: Pueraria Mirifica, Airy Shaw Suvatabhandhu and Butea Superba, Roxb. from various locations in Thailand. ISHS Acta Horticulturae 678

bottom of page